Library
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Finding the cause of a pet's seizures can be difficult. Screening usually starts with a complete history and physical examination, followed by blood and urine tests to look for underlying diseases that can cause seizures. If the cause still cannot be identified, it is possible that they originate within the brain itself and further neurologic testing might be advised.
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Sneezing and nasal discharge can occur for many different reasons, including infection, allergy, foreign body, and tumors. A thorough history and physical exam is the first step in diagnosing the cause of sneezing/nasal discharge. Initial screening tests are outlined, including CBC, biochemistry profile, urinalysis, and coagulation testing. Specific tests and more advanced diagnostics are also summarized.
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Unexplained bleeding is worrisome because it suggests a problem with the body’s blood clotting or coagulation system. Disorders of the coagulation system can arise for many reasons, including shortages of coagulation factors (clotting proteins), a shortage of platelets (a type of blood cell), defective platelets, and serious systemic disease affecting the whole body.
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A pet with vomiting may suffer from an isolated incident, or it could be a sign of more severe problems. If the cause for vomiting is not obvious from history and examination, screening tests may be done to eliminate possible causes and determine a treatment plan. Results can also provide a prognosis for recovery and long-term outlook.
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Weakness can be caused by many different problems and can involve a variety of body systems. Finding the cause of your pet’s weakness starts with a complete history and physical examination. The most commonly recommended screening tests for weakness include complete blood count, serum biochemistry profile, urinalysis, and in a dog, total thyroxine. Additional tests may be recommended based on the results of these screening tests.
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Trypsin-like immunoreactivity (TLI) is a blood test that measures the amount of a pancreatic proenzyme called trypsinogen. This measurement correlates with the amount of pancreatic enzymes released into the intestine to aid in digestion. A low measurement indicates exocrine pancreatic insufficiency.
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Urinalysis is an important part of any comprehensive workup or health screen. It provides information on the urinary system including the kidneys and bladder and also can support diagnosis of metabolic disease, such as diabetes mellitus.
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Cortisol is a stress hormone that is excreted from the body in the urine. Creatinine is a product of muscle metabolism and is normally lost in the urine at a relatively steady rate. The ratio of creatinine to cortisol in the urine can be used to account for the effect of urine concentration on cortisol measurements. Urine cortisol/creatinine ratio is usually evaluated in animals suspected of having Cushing's disease. This test involves the collection of a single urine sample, taken first thing in the morning.
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The presence of protein in urine is called proteinuria, and it may indicate that the kidneys are not working properly. In some situations, proteinuria may even be a sign of kidney failure; however, bleeding or inflammation in the urinary system is a far more common cause. Your veterinarian may recommend further testing if the urinalysis reveals inflammation or bleeding.
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The urine protein/creatinine (UPC) ratio is a test that measures how much protein is being lost through the kidneys. The UPC measures whether protein excretion is greater than expected when compared to the excretion of creatinine. Before the UPC ratio can be interpreted, two other measures of kidney function should be taken: blood urea nitrogen (BUN) and serum creatinine.
